Jie He 何婕

I’m a biostatistician who builds AI-powered tools for clinical research. Most of my work lives at the intersection of rigorous statistical methodology and modern software: the kind of problems where the math matters and so does the engineering.

My PhD research at Boston University analyzes over a billion observations of smartwatch and wearable sensor data from the Electronic Framingham Heart Study, studying how digital biomarkers connect to cognitive aging in older adults. At Vertex Pharmaceuticals, I’m building a multi-agent system that automates the Tables, Figures, and Listings pipeline for clinical trial submissions, with statistical programmers driving LLM agents through a Shiny interface. Before the PhD, I spent three years at Boston Children’s Hospital doing applied biostatistics across pediatric cardiology, hematology, and critical care, where I built R packages, deployed survival models on registry data, and co-authored peer-reviewed publications.

Outside of work, I ski, write, and am always looking for dogs to pet.